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Conformational ensembles of non-peptide ω-conotoxin mimetics and Ca(+2) ion binding to human voltage-gated N-type calcium channel Ca(v)2.2
Chronic neuropathic pain is the most complex and challenging clinical problem of a population that sets a major physical and economic burden at the global level. Ca(2+)-permeable channels functionally orchestrate the processing of pain signals. Among them, N-type voltage-gated calcium channels (VGCC...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498737/ https://www.ncbi.nlm.nih.gov/pubmed/32994894 http://dx.doi.org/10.1016/j.csbj.2020.08.027 |