Docking based screening and molecular dynamics simulations to identify potential selective PDE4B inhibitor

Inhibition of phosphodiesterase 4 (PDE4) is a promising therapeutic approach for the treatment of inflammatory pulmonary disorders, i.e. asthma and chronic obstructive pulmonary disease. However, the treatment with non-selective PDE4 inhibitors is associated with side effects such as nausea and vomi...

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Detalles Bibliográficos
Autores principales: Al-Nema, Mayasah, Gaurav, Anand, Lee, Vannajan Sanghiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498760/
https://www.ncbi.nlm.nih.gov/pubmed/32984588
http://dx.doi.org/10.1016/j.heliyon.2020.e04856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498760/
https://www.ncbi.nlm.nih.gov/pubmed/32984588
http://dx.doi.org/10.1016/j.heliyon.2020.e04856

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