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Cancer-associated fibroblasts of the prostate promote a compliant and more invasive phenotype in benign prostate epithelial cells

Reciprocal interactions between prostate epithelial cells and their adjacent stromal microenvironment not only are essential for tissue homeostasis but also play a key role in tumor development and progression. Malignant transformation is associated with the formation of a reactive stroma where canc...

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Detalles Bibliográficos
Autores principales: Jaeschke, A., Jacobi, A., Lawrence, M.G., Risbridger, G.P., Frydenberg, M., Williams, E.D., Vela, I., Hutmacher, D.W., Bray, L.J., Taubenberger, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498830/
https://www.ncbi.nlm.nih.gov/pubmed/32984808
http://dx.doi.org/10.1016/j.mtbio.2020.100073