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Cancer-associated fibroblasts of the prostate promote a compliant and more invasive phenotype in benign prostate epithelial cells
Reciprocal interactions between prostate epithelial cells and their adjacent stromal microenvironment not only are essential for tissue homeostasis but also play a key role in tumor development and progression. Malignant transformation is associated with the formation of a reactive stroma where canc...
Autores principales: | Jaeschke, A., Jacobi, A., Lawrence, M.G., Risbridger, G.P., Frydenberg, M., Williams, E.D., Vela, I., Hutmacher, D.W., Bray, L.J., Taubenberger, A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498830/ https://www.ncbi.nlm.nih.gov/pubmed/32984808 http://dx.doi.org/10.1016/j.mtbio.2020.100073 |
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