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Potential pharmacodynamic and pharmacokinetic interactions of Nigella Sativa and Trigonella Foenum-graecum with losartan in L-NAME induced hypertensive rats

The objective of this investigation was to study whether Nigella Sativa and Trigonella Foenum-graecum, could modulate the losartan pharmacodynamic (PD) and pharmacokinetic (PK) in experimental L-NAME induced hypertensive rats. For in vivo study, the systolic blood pressure (SBP) of rats was measured...

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Detalles Bibliográficos
Autores principales: Ahad, Abdul, Raish, Mohammad, Bin Jardan, Yousef A., Alam, Mohd Aftab, Al-Mohizea, Abdullah M., Al-Jenoobi, Fahad I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499079/
https://www.ncbi.nlm.nih.gov/pubmed/32994710
http://dx.doi.org/10.1016/j.sjbs.2020.05.009