The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells

Although advanced lipidomics technology facilitates quantitation of intracellular lipid components, little is known about the regulation of lipid metabolism in cancer cells. Here, we show that disruption of the Gdpd3 gene encoding a lysophospholipase D enzyme significantly decreased self-renewal cap...

Descripción completa

Detalles Bibliográficos
Autores principales: Naka, Kazuhito, Ochiai, Ryosuke, Matsubara, Eriko, Kondo, Chie, Yang, Kyung-Min, Hoshii, Takayuki, Araki, Masatake, Araki, Kimi, Sotomaru, Yusuke, Sasaki, Ko, Mitani, Kinuko, Kim, Dong-Wook, Ooshima, Akira, Kim, Seong-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499193/
https://www.ncbi.nlm.nih.gov/pubmed/32943626
http://dx.doi.org/10.1038/s41467-020-18491-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499193/
https://www.ncbi.nlm.nih.gov/pubmed/32943626
http://dx.doi.org/10.1038/s41467-020-18491-9

Ejemplares similares