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The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells
Although advanced lipidomics technology facilitates quantitation of intracellular lipid components, little is known about the regulation of lipid metabolism in cancer cells. Here, we show that disruption of the Gdpd3 gene encoding a lysophospholipase D enzyme significantly decreased self-renewal cap...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499193/ https://www.ncbi.nlm.nih.gov/pubmed/32943626 http://dx.doi.org/10.1038/s41467-020-18491-9 |