Optimization of tamoxifen-induced Cre activity and its effect on immune cell populations

Tamoxifen (TAM) inducible Cre recombinase system is an essential tool to study gene function when early ablation or overexpression can cause developmental defects or embryonic lethality. However, there remains a lack of consensus on the optimal route and dosage of TAM administration in vivo. Here, w...

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Detalles Bibliográficos
Autores principales: Donocoff, Rachel S., Teteloshvili, Nato, Chung, Hyunsoo, Shoulson, Rivka, Creusot, Remi J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499195/
https://www.ncbi.nlm.nih.gov/pubmed/32943672
http://dx.doi.org/10.1038/s41598-020-72179-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499195/
https://www.ncbi.nlm.nih.gov/pubmed/32943672
http://dx.doi.org/10.1038/s41598-020-72179-0

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