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Tumor-derived HMGB1 induces CD62L(dim) neutrophil polarization and promotes lung metastasis in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is highly aggressive, difficult to treat and commonly develops visceral metastasis, including lung metastasis. We observed that High mobility group box 1 protein (HMGB1) was highly expressed in human TNBC and positively correlated with cancer metastasis. The hypo...

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Detalles Bibliográficos
Autores principales: Wang, Zhen, Yang, Chenghui, Li, Lili, Jin, Xiaoyan, Zhang, Zhigang, Zheng, Haiyan, Pan, Jun, Shi, Liyun, Jiang, Zhou, Su, Ke, Li, Baizhou, Shao, Xuan, Qiu, Fuming, Yan, Jun, Huang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499196/
https://www.ncbi.nlm.nih.gov/pubmed/32943604
http://dx.doi.org/10.1038/s41389-020-00267-x