Novel insights into stress-induced susceptibility to influenza: corticosterone impacts interferon-β responses by Mfn2-mediated ubiquitin degradation of MAVS

Although stress has been known to increase the susceptibility of pathogen infection, the underlying mechanism remains elusive. In this study, we reported that restraint stress dramatically enhanced the morbidity and mortality of mice infected with the influenza virus (H1N1) and obviously aggravated...

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Detalles Bibliográficos
Autores principales: Luo, Zhuo, Liu, Li-Fang, Jiang, Ying-Nan, Tang, Lu-Ping, Li, Wen, Ouyang, Shu-Hua, Tu, Long-Fang, Wu, Yan-Ping, Gong, Hai-Biao, Yan, Chang-Yu, Jiang, Shan, Lu, Yu-Hui, Liu, Tongzheng, Jiang, Zhenyou, Kurihara, Hiroshi, Yu, Yang, Yao, Xin-Sheng, Li, Yi-Fang, He, Rong-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499204/
https://www.ncbi.nlm.nih.gov/pubmed/32943610
http://dx.doi.org/10.1038/s41392-020-00238-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499204/
https://www.ncbi.nlm.nih.gov/pubmed/32943610
http://dx.doi.org/10.1038/s41392-020-00238-z

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