Downregulation of the CCL2/CCR2 and CXCL10/CXCR3 axes contributes to antitumor effects in a mouse model of malignant glioma

Glioblastoma multiforme involves glioma stem cells (GSCs) that are resistant to various therapeutic approaches. Here, we studied the importance of paracrine signaling in the glioma microenvironment by focusing on the celecoxib-mediated role of chemokines C–C motif ligand 2 (CCL2), C-X-C ligand 10 (C...

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Detalles Bibliográficos
Autores principales: Shono, Kenji, Yamaguchi, Izumi, Mizobuchi, Yoshifumi, Kagusa, Hiroshi, Sumi, Akiko, Fujihara, Toshitaka, Nakajima, Kohei, Kitazato, Keiko T., Matsuzaki, Kazuhito, Saya, Hideyuki, Takagi, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499211/
https://www.ncbi.nlm.nih.gov/pubmed/32943658
http://dx.doi.org/10.1038/s41598-020-71857-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499211/
https://www.ncbi.nlm.nih.gov/pubmed/32943658
http://dx.doi.org/10.1038/s41598-020-71857-3

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