Reactive oxygen species mediate anlotinib-induced apoptosis via activation of endoplasmic reticulum stress in pancreatic cancer

Anlotinib (AL3818), a novel multi-targeted receptor tyrosine kinase inhibitor, has recently been proven to be an antitumour drug. This study aimed to explore the antitumour effect of anlotinib and its underlying molecular mechanisms in human pancreatic cancer (PC) cells. The anti-proliferative effec...

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Detalles Bibliográficos
Autores principales: Yang, Liguo, Zhou, Xiaoshu, Sun, Jinrui, Lei, Qianghui, Wang, Qi, Pan, Di, Ding, Mingxing, Ding, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499216/
https://www.ncbi.nlm.nih.gov/pubmed/32943607
http://dx.doi.org/10.1038/s41419-020-02938-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499216/
https://www.ncbi.nlm.nih.gov/pubmed/32943607
http://dx.doi.org/10.1038/s41419-020-02938-4

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