Cargando…

Reactive oxygen species mediate anlotinib-induced apoptosis via activation of endoplasmic reticulum stress in pancreatic cancer

Anlotinib (AL3818), a novel multi-targeted receptor tyrosine kinase inhibitor, has recently been proven to be an antitumour drug. This study aimed to explore the antitumour effect of anlotinib and its underlying molecular mechanisms in human pancreatic cancer (PC) cells. The anti-proliferative effec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Liguo, Zhou, Xiaoshu, Sun, Jinrui, Lei, Qianghui, Wang, Qi, Pan, Di, Ding, Mingxing, Ding, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499216/ https://www.ncbi.nlm.nih.gov/pubmed/32943607 http://dx.doi.org/10.1038/s41419-020-02938-4

Ejemplares similares

Endoplasmic Reticulum Stress and Reactive Oxygen Species in Plants
por: Cao, Jiajian, et al.
Publicado: (2022)

Hyperthermia Induces Apoptosis through Endoplasmic Reticulum and Reactive Oxygen Species in Human Osteosarcoma Cells
por: Hou, Chun-Han, et al.
Publicado: (2014)

An Endoplasmic Reticulum Specific Pro‐amplifier of Reactive Oxygen Species in Cancer Cells
por: Xu, Hong‐Gui, et al.
Publicado: (2021)

Berberine alleviates palmitic acid-induced podocyte apoptosis by reducing reactive oxygen species-mediated endoplasmic reticulum stress
por: Xiang, Xing-Yang, et al.
Publicado: (2021)

Cucurbitacin B induces apoptosis in colorectal cells through reactive oxygen species generation and endoplasmic reticulum stress pathways
por: Huang, Jian-Lan, et al.
Publicado: (2023)

Reactive Oxygen Species, Endoplasmic Reticulum Stress and Mitochondrial Dysfunction: The Link with Cardiac Arrhythmogenesis
por: Tse, Gary, et al.
Publicado: (2016)

Selective Activation of Endoplasmic Reticulum Stress by Reactive-Oxygen-Species-Mediated Ochratoxin A-Induced Apoptosis in Tubular Epithelial Cells
por: Khoi, Chong-Sun, et al.
Publicado: (2021)

The C/EBP Homologous Protein (CHOP) Transcription Factor Functions in Endoplasmic Reticulum Stress-Induced Apoptosis and Microbial Infection
por: Hu, Hai, et al.
Publicado: (2019)

Effect of Reactive Oxygen Species on the Endoplasmic Reticulum and Mitochondria during Intracellular Pathogen Infection of Mammalian Cells
por: Lee, Junghwan, et al.
Publicado: (2021)

Protein kinase RNA- like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)- mediated endoplasmic reticulum stress- induced apoptosis in diabetic cardiomyopathy
por: Liu, Zhong-Wei, et al.
Publicado: (2013)

Carnosic Acid Induces Apoptosis Through Reactive Oxygen Species-mediated Endoplasmic Reticulum Stress Induction in Human Renal Carcinoma Caki Cells
por: Min, Kyoung-jin, et al.
Publicado: (2014)

High Concentration of Glucose Increases Reactive Oxygen Species Generation and Apoptosis Induced by Endoplasmic Reticulum Stress Pathway in Rabbit Corneal Epithelial Cells
por: Lu, Jiajun, et al.
Publicado: (2018)

Fucoidan induces Toll-like receptor 4-regulated reactive oxygen species and promotes endoplasmic reticulum stress-mediated apoptosis in lung cancer
por: Hsu, Hsien-Yeh, et al.
Publicado: (2017)

Endoplasmic reticulum stress and apoptosis
por: Faitova, Jitka, et al.
Publicado: (2006)

Silicon dioxide nanoparticles induce insulin resistance through endoplasmic reticulum stress and generation of reactive oxygen species
por: Hu, Hailong, et al.
Publicado: (2019)

Miconazole induces autophagic death in glioblastoma cells via reactive oxygen species-mediated endoplasmic reticulum stress
por: Jung, Hui-Jung, et al.
Publicado: (2021)

Dexamethasone-induced production of reactive oxygen species promotes apoptosis via endoplasmic reticulum stress and autophagy in MC3T3-E1 cells
por: Liu, Wanlin, et al.
Publicado: (2018)

Novel allylated monocarbonyl analogs of curcumin induce mitotic arrest and apoptosis by reactive oxygen species-mediated endoplasmic reticulum stress and inhibition of STAT3
por: Rajamanickam, Vinothkumar, et al.
Publicado: (2017)

Tannic acid alleviates lipopolysaccharide-induced H9C2 cell apoptosis by suppressing reactive oxygen species-mediated endoplasmic reticulum stress
por: Yang, Yan-Ping, et al.
Publicado: (2021)

3β-Hydroxysteroid-Δ24 Reductase (DHCR24) Protects Pancreatic β Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Scavenging Excessive Intracellular Reactive Oxygen Species
por: Li, Yang, et al.
Publicado: (2020)

Curcumin interacts with sildenafil to kill GI tumor cells via endoplasmic reticulum stress and reactive oxygen/ nitrogen species
por: Roberts, Jane L., et al.
Publicado: (2017)

Melatonin Induces Autophagy via Reactive Oxygen Species-Mediated Endoplasmic Reticulum Stress Pathway in Colorectal Cancer Cells
por: Chok, Kian Chung, et al.
Publicado: (2021)

Pazopanib restricts small cell lung cancer proliferation via reactive oxygen species‐mediated endoplasmic reticulum stress
por: Li, Yue, et al.
Publicado: (2022)

Resveratrol induced reactive oxygen species and endoplasmic reticulum stress-mediated apoptosis, and cell cycle arrest in the A375SM malignant melanoma cell line
por: Heo, Jae-Rim, et al.
Publicado: (2018)

Tetrandrine Induces Apoptosis of Human Nasopharyngeal Carcinoma NPC-TW 076 Cells through Reactive Oxygen Species Accompanied by an Endoplasmic Reticulum Stress Signaling Pathway
por: Lin, Ya-Jing, et al.
Publicado: (2016)

Isoalantolactone Induces Reactive Oxygen Species Mediated Apoptosis in Pancreatic Carcinoma PANC-1 Cells
por: Khan, Muhammad, et al.
Publicado: (2012)

Lithium chloride induces apoptosis by activating endoplasmic reticulum stress in pancreatic cancer
por: Wu, Hao, et al.
Publicado: (2023)

Curcumin enhances the effects of irinotecan on colorectal cancer cells through the generation of reactive oxygen species and activation of the endoplasmic reticulum stress pathway
por: Huang, Yan-Feng, et al.
Publicado: (2017)

Metallic wear debris collected from patients induces apoptosis in rat primary osteoblasts via reactive oxygen species-mediated mitochondrial dysfunction and endoplasmic reticulum stress
por: Yang, Fei, et al.
Publicado: (2019)

Reactive oxygen species‐mediated endoplasmic reticulum stress response induces apoptosis of Mycobacterium avium‐infected macrophages by activating regulated IRE1‐dependent decay pathway
por: Go, Dam, et al.
Publicado: (2019)

Dose-dependent effects of cisplatin on the severity of testicular injury in Sprague Dawley rats: reactive oxygen species and endoplasmic reticulum stress
por: Soni, Kiran Kumar, et al.
Publicado: (2016)

LNS8801 inhibits Acute Myeloid Leukemia by Inducing the Production of Reactive Oxygen Species and Activating the Endoplasmic Reticulum Stress Pathway
por: Lee, Inyoung, et al.
Publicado: (2023)

5-Nitro-2-(3-phenylpropylamino) benzoic acid induces apoptosis of human lens epithelial cells via reactive oxygen species and endoplasmic reticulum stress through the mitochondrial apoptosis pathway
por: Niu, Lingzhi, et al.
Publicado: (2021)

Involvement of Endoplasmic Reticulum Stress in Capsaicin-Induced Apoptosis of Human Pancreatic Cancer Cells
por: Lin, Shengzhang, et al.
Publicado: (2013)

Mycobacterial HBHA induces endoplasmic reticulum stress-mediated apoptosis through the generation of reactive oxygen species and cytosolic Ca(2+) in murine macrophage RAW 264.7 cells
por: Choi, J-A, et al.
Publicado: (2013)

l-Carnitine reduces reactive oxygen species/endoplasmic reticulum stress and maintains mitochondrial function during autophagy-mediated cell apoptosis in perfluorooctanesulfonate-treated renal tubular cells
por: Lee, Yuan-Chii Gladys, et al.
Publicado: (2022)

Downregulation of Reactive Oxygen Species in Apoptosis
por: Jeong, Chul-Ho, et al.
Publicado: (2016)

Evaluation of mitochondrial bioenergetics, dynamics, endoplasmic reticulum-mitochondria crosstalk, and reactive oxygen species in fibroblasts from patients with complex I deficiency
por: Leipnitz, Guilhian, et al.
Publicado: (2018)

Calcium Release from Endoplasmic Reticulum Involves Calmodulin-Mediated NADPH Oxidase-Derived Reactive Oxygen Species Production in Endothelial Cells
por: Sakurada, Ryugo, et al.
Publicado: (2019)

Exogenous spermidine alleviates diabetic cardiomyopathy via suppressing reactive oxygen species, endoplasmic reticulum stress, and Pannexin-1-mediated ferroptosis
por: Sun, Jian, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_nb4f969422jo5ukk2ihhkesi6b