Multiple capsid protein binding sites mediate selective packaging of the alphavirus genomic RNA

The alphavirus capsid protein (Cp) selectively packages genomic RNA (gRNA) into the viral nucleocapsid to produce infectious virus. Using photoactivatable ribonucleoside crosslinking and an innovative biotinylated Cp retrieval method, here we comprehensively define binding sites for Semliki Forest v...

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Detalles Bibliográficos
Autores principales: Brown, Rebecca S., Anastasakis, Dimitrios G., Hafner, Markus, Kielian, Margaret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499256/
https://www.ncbi.nlm.nih.gov/pubmed/32943634
http://dx.doi.org/10.1038/s41467-020-18447-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499256/
https://www.ncbi.nlm.nih.gov/pubmed/32943634
http://dx.doi.org/10.1038/s41467-020-18447-z

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