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Bisoprolol responses (PK/PD) in hypertensive patients: A cytochrome P450 (CYP) 2D6 targeted polymorphism study

BACKGROUND: Bisoprolol is an effective β1-adrenergic blocker, an inter-individual genetic variability was recorded in its response. This study aimed at investigating the association of CYP2D6*2A (rs1080985) and CYP2D6*10 (rs1065852) single-nucleotide polymorphism (SNP) with Bisoprolol response in ca...

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Detalles Bibliográficos
Autores principales: Mohammed Alkreathy, Huda, Mohammed Eid Alsayyid, Khlood, Alaama, Jumana Y., Al Ghalayini, Kamal, Karim, Shahid, Esmat, Ahmed, Damanhouri, Zoheir A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499297/
https://www.ncbi.nlm.nih.gov/pubmed/32994732
http://dx.doi.org/10.1016/j.sjbs.2020.06.022