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Bisoprolol responses (PK/PD) in hypertensive patients: A cytochrome P450 (CYP) 2D6 targeted polymorphism study
BACKGROUND: Bisoprolol is an effective β1-adrenergic blocker, an inter-individual genetic variability was recorded in its response. This study aimed at investigating the association of CYP2D6*2A (rs1080985) and CYP2D6*10 (rs1065852) single-nucleotide polymorphism (SNP) with Bisoprolol response in ca...
Autores principales: | Mohammed Alkreathy, Huda, Mohammed Eid Alsayyid, Khlood, Alaama, Jumana Y., Al Ghalayini, Kamal, Karim, Shahid, Esmat, Ahmed, Damanhouri, Zoheir A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499297/ https://www.ncbi.nlm.nih.gov/pubmed/32994732 http://dx.doi.org/10.1016/j.sjbs.2020.06.022 |
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