Single-cell RNA-seq identifies unique transcriptional landscapes of human nucleus pulposus and annulus fibrosus cells

Intervertebral disc (IVD) disease (IDD) is a complex, multifactorial disease. While various aspects of IDD progression have been reported, the underlying molecular pathways and transcriptional networks that govern the maintenance of healthy nucleus pulposus (NP) and annulus fibrosus (AF) have not be...

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Detalles Bibliográficos
Autores principales: Fernandes, Lorenzo M., Khan, Nazir M., Trochez, Camila M., Duan, Meixue, Diaz-Hernandez, Martha E., Presciutti, Steven M., Gibson, Greg, Drissi, Hicham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499307/
https://www.ncbi.nlm.nih.gov/pubmed/32943704
http://dx.doi.org/10.1038/s41598-020-72261-7