Assessment of proton-coupled conformational dynamics of SARS and MERS coronavirus papain-like proteases: Implication for designing broad-spectrum antiviral inhibitors

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Broad-spectrum antiviral drugs are urgently needed to stop the Coronavirus Disease 2019 pandemic and prevent future ones. The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is related to the SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV), which have caused t...

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Detalles Bibliográficos
Autores principales: Henderson, Jack A., Verma, Neha, Harris, Robert C., Liu, Ruibin, Shen, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2020
Materias:
ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499820/
https://www.ncbi.nlm.nih.gov/pubmed/32962355
http://dx.doi.org/10.1063/5.0020458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499820/
https://www.ncbi.nlm.nih.gov/pubmed/32962355
http://dx.doi.org/10.1063/5.0020458

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