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Whole-exome sequencing reveals ANO8 as a genetic risk factor for intrahepatic cholestasis of pregnancy

BACKGROUND: Intrahepatic cholestasis of pregnancy (ICP) is characterized by pruritus and cholestasis in late pregnancy and results in adverse pregnancy outcomes, including preterm delivery and birth weight, which are affected by the genetic and environmental background. However, until now, the genet...

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Detalles Bibliográficos
Autores principales: Liu, Xianxian, Lai, Hua, Zeng, Xiaoming, Xin, Siming, Nie, Liju, Liang, Zhenyi, Wu, Meiling, Chen, Yu, Zheng, Jiusheng, Zou, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499841/
https://www.ncbi.nlm.nih.gov/pubmed/32942997
http://dx.doi.org/10.1186/s12884-020-03240-z