Removing reference bias and improving indel calling in ancient DNA data analysis by mapping to a sequence variation graph

BACKGROUND: During the last decade, the analysis of ancient DNA (aDNA) sequence has become a powerful tool for the study of past human populations. However, the degraded nature of aDNA means that aDNA molecules are short and frequently mutated by post-mortem chemical modifications. These features de...

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Detalles Bibliográficos
Autores principales: Martiniano, Rui, Garrison, Erik, Jones, Eppie R., Manica, Andrea, Durbin, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499850/
https://www.ncbi.nlm.nih.gov/pubmed/32943086
http://dx.doi.org/10.1186/s13059-020-02160-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499850/
https://www.ncbi.nlm.nih.gov/pubmed/32943086
http://dx.doi.org/10.1186/s13059-020-02160-7

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