Cargando…
Removing reference bias and improving indel calling in ancient DNA data analysis by mapping to a sequence variation graph
BACKGROUND: During the last decade, the analysis of ancient DNA (aDNA) sequence has become a powerful tool for the study of past human populations. However, the degraded nature of aDNA means that aDNA molecules are short and frequently mutated by post-mortem chemical modifications. These features de...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499850/ https://www.ncbi.nlm.nih.gov/pubmed/32943086 http://dx.doi.org/10.1186/s13059-020-02160-7 |