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ALDH-1-positive cells exhibited a radioresistant phenotype that was enhanced with hypoxia in cervical cancer

BACKGROUND: We have previously found there was a small subpopulation of cells with cancer stem cell-like phenotype ALDH-1 in cervical cancer. Radiotherapy has been applied in most of the cervical cancer. However,the mechanisms underlying radioresistance still remained elusive. Our study is to explor...

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Detalles Bibliográficos
Autores principales: Yao, Tingting, Weng, Xueling, Yao, Yao, Huang, Chunxian, Li, Jing, Peng, Yongpai, Lin, Rongchun, Lin, Zhongqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499852/
https://www.ncbi.nlm.nih.gov/pubmed/32942996
http://dx.doi.org/10.1186/s12885-020-07337-8