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Smoking-associated increase in mucins 1 and 4 in human airways

RATIONALE: Smoking-related chronic obstructive pulmonary disease (COPD) is associated with dysregulated production of mucus. Mucins (MUC) are important both for mucus secretion and epithelial defense. We have examined the distribution of MUC1 and MUC4 in the airway epithelial cells of never-smokers...

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Detalles Bibliográficos
Autores principales: Merikallio, Heta, Kaarteenaho, Riitta, Lindén, Sara, Padra, Médea, Karimi, Reza, Li, Chuan-Xing, Lappi-Blanco, Elisa, Wheelock, Åsa M., Sköld, Magnus C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499856/
https://www.ncbi.nlm.nih.gov/pubmed/32948202
http://dx.doi.org/10.1186/s12931-020-01498-7