Osteopontin/secreted phosphoprotein-1 behaves as a molecular brake regulating the neuroinflammatory response to chronic viral infection

BACKGROUND: Osteopontin (OPN) as a secreted signaling protein is dramatically induced in response to cellular injury and neurodegeneration. Microglial inflammatory responses in the brain are tightly associated with the neuropathologic hallmarks of neurodegenerative disease, but understanding of the...

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Detalles Bibliográficos
Autores principales: Mahmud, Farina J., Du, Yong, Greif, Elizabeth, Boucher, Thomas, Dannals, Robert F., Mathews, William B., Pomper, Martin G., Sysa-Shah, Polina, Metcalf Pate, Kelly A., Lyons, Claire, Carlson, Bess, Chacona, Maria, Brown, Amanda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499959/
https://www.ncbi.nlm.nih.gov/pubmed/32943056
http://dx.doi.org/10.1186/s12974-020-01949-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499959/
https://www.ncbi.nlm.nih.gov/pubmed/32943056
http://dx.doi.org/10.1186/s12974-020-01949-4

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