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Microglial-associated responses to comorbid amyloid pathology and hyperhomocysteinemia in an aged knock-in mouse model of Alzheimer’s disease

BACKGROUND: Elevated blood homocysteine levels, termed hyperhomocysteinemia (HHcy), is a prevalent risk factor for Alzheimer’s disease (AD) in elderly populations. While dietary supplementation of B-vitamins is a generally effective method to lower homocysteine levels, there is little if any benefit...

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Detalles Bibliográficos
Autores principales:	Braun, David J., Dimayuga, Edgardo, Morganti, Josh M., Van Eldik, Linda J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7499995/ https://www.ncbi.nlm.nih.gov/pubmed/32943069 http://dx.doi.org/10.1186/s12974-020-01938-7

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