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The Ibr-7 derivative of ibrutinib radiosensitizes pancreatic cancer cells by downregulating p-EGFR

BACKGROUND: Radiotherapy is one of the main treatments for pancreatic cancer, but radiation resistance limits its clinical application. As a result, novel therapeutic agents to improve radiosensitivity are urgently needed. This study aimed to investigate the effect of Ibr-7 (a derivative of ibrutini...

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Detalles Bibliográficos
Autores principales: Tan, Biqin, Dong, Rong, Zhang, Bo, Yan, Youyou, Li, Qingyu, Wang, Fei, Lin, Nengming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500014/
https://www.ncbi.nlm.nih.gov/pubmed/32963499
http://dx.doi.org/10.1186/s12935-020-01548-6