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The Ibr-7 derivative of ibrutinib radiosensitizes pancreatic cancer cells by downregulating p-EGFR
BACKGROUND: Radiotherapy is one of the main treatments for pancreatic cancer, but radiation resistance limits its clinical application. As a result, novel therapeutic agents to improve radiosensitivity are urgently needed. This study aimed to investigate the effect of Ibr-7 (a derivative of ibrutini...
Autores principales: | Tan, Biqin, Dong, Rong, Zhang, Bo, Yan, Youyou, Li, Qingyu, Wang, Fei, Lin, Nengming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500014/ https://www.ncbi.nlm.nih.gov/pubmed/32963499 http://dx.doi.org/10.1186/s12935-020-01548-6 |
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