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Transcriptomic, Proteomic, and Functional Long-Term Characterization of Multicellular Three-Dimensional Human Liver Microtissues

Three-Dimensional (3D) liver microtissues, specifically prepared from primary human hepatocytes (PHH) in coculture with nonparenchymal cells (NPCs), have been shown to be a valuable tool for in vitro toxicology. However, a lack of thorough characterization on a functional, transcriptomic, and proteo...

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Detalles Bibliográficos
Autores principales: Messner, Simon, Fredriksson, Lisa, Lauschke, Volker M., Roessger, Katrin, Escher, Claudia, Bober, Magdalena, Kelm, Jens M., Ingelman-Sundberg, Magnus, Moritz, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500040/
https://www.ncbi.nlm.nih.gov/pubmed/32953943
http://dx.doi.org/10.1089/aivt.2017.0022