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Transcriptomic, Proteomic, and Functional Long-Term Characterization of Multicellular Three-Dimensional Human Liver Microtissues
Three-Dimensional (3D) liver microtissues, specifically prepared from primary human hepatocytes (PHH) in coculture with nonparenchymal cells (NPCs), have been shown to be a valuable tool for in vitro toxicology. However, a lack of thorough characterization on a functional, transcriptomic, and proteo...
Autores principales: | Messner, Simon, Fredriksson, Lisa, Lauschke, Volker M., Roessger, Katrin, Escher, Claudia, Bober, Magdalena, Kelm, Jens M., Ingelman-Sundberg, Magnus, Moritz, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500040/ https://www.ncbi.nlm.nih.gov/pubmed/32953943 http://dx.doi.org/10.1089/aivt.2017.0022 |
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