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Biological evaluation of pyrazolyl-urea and dihydro-imidazo-pyrazolyl-urea derivatives as potential anti-angiogenetic agents in the treatment of neuroblastoma

Pyrazolyl-urea and dihydro-imidazo-pyrazolyl-urea compounds (STIRUR 13, STIRUR 41 and BUR 12) have been demonstrated to exert a strong inhibitory effect on interleukin 8 or N-formyl-methionyl-leucyl-phenylalanine-induced chemotaxis of human neutrophils. Since the migration of cancer cells is compara...

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Detalles Bibliográficos
Autores principales: Marengo, Barbara, Meta, Elda, Brullo, Chiara, De Ciucis, Chiara, Colla, Renata, Speciale, Andrea, Garbarino, Ombretta, Bruno, Olga, Domenicotti, Cinzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500105/
https://www.ncbi.nlm.nih.gov/pubmed/32973970
http://dx.doi.org/10.18632/oncotarget.27733