Validation of a Combined Transcriptome and T Cell Receptor Alpha/Beta (TRA/TRB) Repertoire Assay at the Single Cell Level for Paucicellular Samples

Transcriptomics can be combined with TRA and TRB clonotype analysis at the single cell level. The aim of this study was to validate this approach on the ICELL8 Single-Cell system and to evaluate its usefulness to analyse clinical paucicellular samples. For this purpose, we carefully selected T cell...

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Detalles Bibliográficos
Autores principales: Litjens, Nicolle H. R., Langerak, Anton W., van der List, Amy C. J., Klepper, Mariska, de Bie, Maaike, Azmani, Zakia, den Dekker, Alexander T., Brouwer, Rutger W. W., Betjes, Michiel G. H., Van IJcken, Wilfred F. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500136/
https://www.ncbi.nlm.nih.gov/pubmed/33013853
http://dx.doi.org/10.3389/fimmu.2020.01999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500136/
https://www.ncbi.nlm.nih.gov/pubmed/33013853
http://dx.doi.org/10.3389/fimmu.2020.01999

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