Epac1 Requires AMPK Phosphorylation to Regulate HMGB1 in the Retinal Vasculature

PURPOSE: To investigate whether AMP-activated protein kinase (AMPK) is required for the reduction of high mobility group box 1 (HMGB1) by exchange proteins activated by cAMP 1 (Epac1) in the retinal vasculature. METHODS: We measured AMPK phosphorylation in normal and diabetic Epac1 floxed and cdh5/E...

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Detalles Bibliográficos
Autores principales: Jiang, Youde, Steinle, Jena J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500149/
https://www.ncbi.nlm.nih.gov/pubmed/32940662
http://dx.doi.org/10.1167/iovs.61.11.33

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500149/
https://www.ncbi.nlm.nih.gov/pubmed/32940662
http://dx.doi.org/10.1167/iovs.61.11.33

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