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Epac1 Requires AMPK Phosphorylation to Regulate HMGB1 in the Retinal Vasculature
PURPOSE: To investigate whether AMP-activated protein kinase (AMPK) is required for the reduction of high mobility group box 1 (HMGB1) by exchange proteins activated by cAMP 1 (Epac1) in the retinal vasculature. METHODS: We measured AMPK phosphorylation in normal and diabetic Epac1 floxed and cdh5/E...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500149/ https://www.ncbi.nlm.nih.gov/pubmed/32940662 http://dx.doi.org/10.1167/iovs.61.11.33 |