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IL-17A Neutralization Improves the Neurological Outcome of Mice With Ischemic Stroke and Inhibits Caspase-12-Dependent Apoptosis

We previously reported that the levels of astrocyte-derived interleukin-17A (IL-17A) increased both in the peri-infarct region and cerebrospinal fluid (CSF) of mice with 1-h middle cerebral artery (MCA) occlusion/12-h reperfusion (1-h MCAO/R 12 h)-induced ischemic stroke. However, the effects of IL-...

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Detalles Bibliográficos
Autores principales: Dai, Qingqing, Han, Song, Liu, Ting, Zheng, Jiayin, Liu, Cui, Li, Junfa, Li, Shujuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500152/
https://www.ncbi.nlm.nih.gov/pubmed/33101005
http://dx.doi.org/10.3389/fnagi.2020.00274