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Functional Profiling of CFTR-Directed Therapeutics Using Pediatric Patient-Derived Nasal Epithelial Cell Models

Functional profiling of CFTR-directed therapeutics offers the potential to provide significant benefits to young people with cystic fibrosis (CF). However, the development of 2D airway epithelial cell models for individual response tests in CF children remains a central task. The objective of this s...

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Detalles Bibliográficos
Autores principales: Park, Jeffrey KiHyun, Shrivastava, Anura, Zhang, Chengkang, Pollok, Brian A., Finkbeiner, Walter E., Gibb, Elizabeth R., Ly, Ngoc P., Illek, Beate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500161/
https://www.ncbi.nlm.nih.gov/pubmed/33014932
http://dx.doi.org/10.3389/fped.2020.00536