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Functional Profiling of CFTR-Directed Therapeutics Using Pediatric Patient-Derived Nasal Epithelial Cell Models
Functional profiling of CFTR-directed therapeutics offers the potential to provide significant benefits to young people with cystic fibrosis (CF). However, the development of 2D airway epithelial cell models for individual response tests in CF children remains a central task. The objective of this s...
Autores principales: | Park, Jeffrey KiHyun, Shrivastava, Anura, Zhang, Chengkang, Pollok, Brian A., Finkbeiner, Walter E., Gibb, Elizabeth R., Ly, Ngoc P., Illek, Beate |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500161/ https://www.ncbi.nlm.nih.gov/pubmed/33014932 http://dx.doi.org/10.3389/fped.2020.00536 |
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