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Crizanlizumab and comparators for adults with sickle cell disease: a systematic review and network meta-analysis

OBJECTIVES: Treatment options for preventing vaso-occlusive crises (VOC) among patients with sickle cell disease (SCD) are limited, especially if hydroxyurea treatment has failed or is contraindicated. A systematic literature review (SLR) and network meta-analysis (NMA) were conducted to evaluate th...

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Detalles Bibliográficos
Autores principales: Thom, Howard, Jansen, Jeroen, Shafrin, Jason, Zhao, Lauren, Joseph, George, Cheng, Hung-Yuan, Gupta, Subhajit, Shah, Nirmish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500297/
https://www.ncbi.nlm.nih.gov/pubmed/32948541
http://dx.doi.org/10.1136/bmjopen-2019-034147