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Transcriptomics predicts compound synergy in drug and natural product treated glioblastoma cells

Pathway analysis is an informative method for comparing and contrasting drug-induced gene expression in cellular systems. Here, we define the effects of the marine natural product fucoxanthin, separately and in combination with the prototypic phosphatidylinositol 3-kinase (PI3K) inhibitor LY-294002,...

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Detalles Bibliográficos
Autores principales: Pruteanu, Lavinia-Lorena, Kopanitsa, Liliya, Módos, Dezső, Kletnieks, Edgars, Samarova, Elena, Bender, Andreas, Gomez, Leonardo Dario, Bailey, David Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500592/
https://www.ncbi.nlm.nih.gov/pubmed/32946518
http://dx.doi.org/10.1371/journal.pone.0239551