BioPETsurv: Methodology and open source software to evaluate biomarkers for prognostic enrichment of time-to-event clinical trials

Biomarkers can be used to enrich a clinical trial for patients at higher risk for an outcome, a strategy termed "prognostic enrichment." Methodology is needed to evaluate biomarkers for prognostic enrichment of trials with time-to-event endpoints such as survival. Key considerations when c...

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Detalles Bibliográficos
Autores principales: Cheng, Si, Kerr, Kathleen F., Thiessen-Philbrook, Heather, Coca, Steven G., Parikh, Chirag R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500596/
https://www.ncbi.nlm.nih.gov/pubmed/32946505
http://dx.doi.org/10.1371/journal.pone.0239486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500596/
https://www.ncbi.nlm.nih.gov/pubmed/32946505
http://dx.doi.org/10.1371/journal.pone.0239486

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