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BioPETsurv: Methodology and open source software to evaluate biomarkers for prognostic enrichment of time-to-event clinical trials
Biomarkers can be used to enrich a clinical trial for patients at higher risk for an outcome, a strategy termed "prognostic enrichment." Methodology is needed to evaluate biomarkers for prognostic enrichment of trials with time-to-event endpoints such as survival. Key considerations when c...
Autores principales: | Cheng, Si, Kerr, Kathleen F., Thiessen-Philbrook, Heather, Coca, Steven G., Parikh, Chirag R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500596/ https://www.ncbi.nlm.nih.gov/pubmed/32946505 http://dx.doi.org/10.1371/journal.pone.0239486 |
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