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The p150 Isoform of ADAR1 Blocks Sustained RLR signaling and Apoptosis during Influenza Virus Infection

Signaling through retinoic acid inducible gene I (RIG-I) like receptors (RLRs) is tightly regulated, with activation occurring upon sensing of viral nucleic acids, and suppression mediated by negative regulators. Under homeostatic conditions aberrant activation of melanoma differentiation-associated...

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Detalles Bibliográficos
Autores principales: Vogel, Olivia A., Han, Julianna, Liang, Chieh-Yu, Manicassamy, Santhakumar, Perez, Jasmine T., Manicassamy, Balaji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500621/
https://www.ncbi.nlm.nih.gov/pubmed/32898178
http://dx.doi.org/10.1371/journal.ppat.1008842