Post-tetanic potentiation lowers the energy barrier for synaptic vesicle fusion independently of Synaptotagmin-1

Previously, we showed that modulation of the energy barrier for synaptic vesicle fusion boosts release rates supralinearly (Schotten, 2015). Here we show that mouse hippocampal synapses employ this principle to trigger Ca(2+)-dependent vesicle release and post-tetanic potentiation (PTP). We assess e...

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Detalles Bibliográficos
Autores principales: Huson, Vincent, Meijer, Marieke, Dekker, Rien, ter Veer, Mirelle, Ruiter, Marvin, van Weering, Jan RT, Verhage, Matthijs, Cornelisse, Lennart Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500951/
https://www.ncbi.nlm.nih.gov/pubmed/32831174
http://dx.doi.org/10.7554/eLife.55713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7500951/
https://www.ncbi.nlm.nih.gov/pubmed/32831174
http://dx.doi.org/10.7554/eLife.55713

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