Autophagy induction promotes renal cyst growth in polycystic kidney disease

BACKGROUND: Polycystic kidney disease (PKD) involves renal cysts arising from proliferating tubular cells. Autophagy has been recently suggested as a potential therapeutic target in PKD, and mammalian target of rapamycin (mTOR) is a key negative regulator of autophagy. However, the effect of autopha...

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Detalles Bibliográficos
Autores principales: Lee, Eun Ji, Ko, Je Yeong, Oh, Sumin, Jun, Jaehee, Mun, Hyowon, Lim, Chae Ji, Seo, Seungwoon, Ko, Hyuk Wan, Kim, Hyunho, Oh, Yun Kyu, Ahn, Curie, Kang, Minyong, Kim, Min Jung, Yoo, Kyung Hyun, Oh, Goo Taeg, Park, Jong Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501056/
https://www.ncbi.nlm.nih.gov/pubmed/32949996
http://dx.doi.org/10.1016/j.ebiom.2020.102986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501056/
https://www.ncbi.nlm.nih.gov/pubmed/32949996
http://dx.doi.org/10.1016/j.ebiom.2020.102986

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