Endothelial damage and a thin intercellular fibrin network promote haemorrhage in acute promyelocytic leukaemia

BACKGROUND: The role of vascular endothelium in acute promyelocytic leukaemia (APL) remains unknown. We aimed to investigate the mechanisms by which APL cells interact with endothelial cells (ECs) and to further explore how the endothelium affects bleeding as well as therapeutic interventions. METHO...

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Detalles Bibliográficos
Autores principales: Wang, Chunxu, Yu, Muxin, Zhou, Peng, Li, Baorong, Liu, Yingmiao, Wang, Lixiu, Chen, Xiaojing, Du, Jingwen, Wang, Yufeng, Zhang, Jinming, Jing, Haijiao, Feng, Yiming, Zhang, Yue, Li, Yueyue, Dong, Zengxiang, Fang, Shaohong, Novakovic, Valerie A, Zhou, Jin, Shi, Jialan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501057/
https://www.ncbi.nlm.nih.gov/pubmed/32949998
http://dx.doi.org/10.1016/j.ebiom.2020.102992

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501057/
https://www.ncbi.nlm.nih.gov/pubmed/32949998
http://dx.doi.org/10.1016/j.ebiom.2020.102992

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