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A novel, rapid (within hours) culture-free diagnostic method for detecting live Mycobacterium tuberculosis with high sensitivity

BACKGROUND: Nucleic acid amplification tests (NAATs) are widely used to diagnose tuberculosis (TB), but cannot discriminate live bacilli from dead bacilli. Live bacilli can be isolated by culture methods, but this is time-consuming. We developed a de novo TB diagnostic method that detects only live...

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Detalles Bibliográficos
Autores principales: Wang, Wen-Hung, Takeuchi, Rikiya, Jain, Shu-Huei, Jiang, Yong-Huang, Watanuki, Sonoko, Ohtaki, Yoshiharu, Nakaishi, Kazunari, Watabe, Satoshi, Lu, Po-Liang, Ito, Etsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501073/
https://www.ncbi.nlm.nih.gov/pubmed/32949995
http://dx.doi.org/10.1016/j.ebiom.2020.103007