Click chemistry compared to thiol chemistry for the synthesis of site-selective glycoconjugate vaccines using CRM(197) as carrier protein

Conjugation chemistry is one of the main parameters affecting immunogenicity of glycoconjugate vaccines and a rational approach toward a deeper understanding of their mechanism of action will greatly benefit from highly-defined and well-characterized structures. Herein, different conjugation methods...

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Detalles Bibliográficos
Autores principales: Stefanetti, G., Allan, M., Usera, A., Micoli, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501094/
https://www.ncbi.nlm.nih.gov/pubmed/32535667
http://dx.doi.org/10.1007/s10719-020-09930-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501094/
https://www.ncbi.nlm.nih.gov/pubmed/32535667
http://dx.doi.org/10.1007/s10719-020-09930-2

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