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Envelope Protein Ubiquitination Drives Zika Virus Entry and Pathogenesis

Zika virus (ZIKV) belongs to the Flaviviridae family and is related to other viruses that cause human diseases. Unlike other flaviviruses, ZIKV infection can cause congenital neurologic disorders and replicates efficiently in reproductive tissues(1–3,). Here, we show that ZIKV envelope (E) protein i...

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Detalles Bibliográficos
Autores principales: Giraldo, Maria I., Xia, Hongjie, Aguilera-Aguirre, Leopoldo, Hage, Adam, van Tol, Sarah, Shan, Chao, Xie, Xuping, Sturdevant, Gail L., Robertson, Shelly J., McNally, Kristin L., Meade-White, Kimberly, Azar, Sasha R., Rossi, Shannan L., Maury, Wendy, Woodson, Michael, Ramage, Holly, Johnson, Jeffrey R., Krogan, Nevan J., Morais, Marc C., Best, Sonja M., Shi, Pei-Yong, Rajsbaum, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501154/
https://www.ncbi.nlm.nih.gov/pubmed/32641828
http://dx.doi.org/10.1038/s41586-020-2457-8