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Multiplex flow magnetic tweezers reveal rare enzymatic events with single molecule precision

The application of forces and torques on the single molecule level has transformed our understanding of the dynamic properties of biomolecules, but rare intermediates have remained difficult to characterize due to limited throughput. Here, we describe a method that provides a 100-fold improvement in...

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Detalles Bibliográficos
Autores principales: Agarwal, Rohit, Duderstadt, Karl E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501243/
https://www.ncbi.nlm.nih.gov/pubmed/32948754
http://dx.doi.org/10.1038/s41467-020-18456-y