Cargando…

Expression profiles of proton-sensing G-protein coupled receptors in common skin tumors

The proton-sensing GPCRs (pH-GPCRs) GPR4 (GPR19), TDAG8 (GPR65, T-cell death associated gene 8), OGR1 (GPR68, ovarian cancer GPCR1), and G2A (GPR132, G2 accumulation protein) are involved in sensing and transducing changes in extracellular pH (pH(e)). Extracellular acidification is a central hallmar...

Descripción completa

Detalles Bibliográficos
Autores principales: Klatt, Wybke, Wallner, Susanne, Brochhausen, Christoph, Stolwijk, Judith A., Schreml, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501253/
https://www.ncbi.nlm.nih.gov/pubmed/32948783
http://dx.doi.org/10.1038/s41598-020-71700-9