Protein kinase D1 phosphorylation of KAT7 enhances its protein stability and promotes replication licensing and cell proliferation

The histone acetyltransferase (HAT) KAT7/HBO1/MYST2 plays a crucial role in the pre-replication complex (pre-RC) formation, DNA replication and cell proliferation via acetylation of histone H4 and H3. In a search for protein kinase D1 (PKD1)-interacting proteins, we have identified KAT7 as a potenti...

Descripción completa

Detalles Bibliográficos
Autores principales: Liang, Yao, Su, Yuanyuan, Xu, Chenzhong, Zhang, Na, Liu, Doudou, Li, Guodong, Tong, Tanjun, Chen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501302/
https://www.ncbi.nlm.nih.gov/pubmed/33014433
http://dx.doi.org/10.1038/s41420-020-00323-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7501302/
https://www.ncbi.nlm.nih.gov/pubmed/33014433
http://dx.doi.org/10.1038/s41420-020-00323-w

Ejemplares similares